Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regulation of Notch signaling by glycosylation.

Current opinion in structural biology - 1 Oct 2007

Stanley Pamela

Abstract excerpt

Notch receptors are approximately 300 kDa cell surface glycoproteins whose activation by Notch ligands regulates cell fate decisions in the metazoa. The extracellular domain of Notch receptors has many epidermal growth factor like repeats that are glycosylated with O-fucose and O-glucose glycans...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carbohydrate Sequence
Share to Drosophila
Share to Fucose

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Insect

Share to Glycosylation

Share to Mammals

Share to N-Acetylglucosaminyltransferases

Share to Receptors, Notch

Source

Open in PubMed Open full text

Identifiers

PMID: 17964136
DOI: 10.1016/j.sbi.2007.09.007
PMCID: PMC2141538

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17964136-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulation of Notch signaling by glycosylation.PMID 17964136Read ↗

Roles of O-fucose glycans in notch signaling revealed by mutant mice.Semantic proximity Read ↗

Contribution of extracellular O-GlcNAc to the stability of folded epidermal growth factor-like domains and Notch1 trafficking.Semantic proximity Read ↗

Notch signaling in development and disease.Semantic proximity Read ↗

Regulation of notch signaling by o-linked fucose.Semantic proximity Read ↗

Two pathways for importing GDP-fucose into the endoplasmic reticulum lumen function redundantly in the O-fucosylation of Notch in Drosophila.Semantic proximity Read ↗

Highly conserved O-fucose sites have distinct effects on Notch1 function.Semantic proximity Read ↗

Diseases related to Notch glycosylationSemantic proximity Read ↗

Negative regulation of notch signaling by xylose.Semantic proximity Read ↗

Notch deficiency implicated in the pathogenesis of congenital disorder of glycosylation IIc.Semantic proximity Read ↗

Functional analysis of glycosylation using Drosophila melanogaster.Semantic proximity Read ↗

Rescue of Notch signaling in cells incapable of GDP-L-fucose synthesis by gap junction transfer of GDP-L-fucose in Drosophila.Semantic proximity Read ↗

Protein O-GlcNAcylation is required for fibroblast growth factor signaling in Drosophila.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.