Article
Efficient linkage mapping using exome capture and extreme QTL in schistosome parasites.
BMC genomics - 21 Jul 2014
Chevalier Frédéric D, Valentim Claudia L L, LoVerde Philip T, Anderson Timothy J C
Abstract excerpt
BACKGROUND: Identification of parasite genes that underlie traits such as drug resistance and host specificity is challenging using classical linkage mapping approaches. Extreme QTL (X-QTL) methods, originally developed by rodent malaria and yeast researchers, promise to increase the power and simplify logistics of linkage mapping in experimental crosses of schistosomes (or other helminth parasites), because many...
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