Article
Private selective sweeps identified from next-generation pool-sequencing reveal convergent pathways under selection in two inbred Schistosoma mansoni strains.
PLoS neglected tropical diseases - 1 Jan 2013
Clément Julie A J, Toulza Eve, Gautier Mathieu, Parrinello Hugues, Roquis David, Boissier Jérôme, Rognon Anne, Moné Hélène, Mouahid Gabriel, Buard Jérôme, Mitta Guillaume, Grunau Christoph
Abstract excerpt
BACKGROUND: The trematode flatworms of the genus Schistosoma, the causative agents of schistosomiasis, are among the most prevalent parasites in humans, affecting more than 200 million people worldwide. In this study, we focused on two well-characterized strains of S. mansoni, to explore signatures of selection. Both strains are highly inbred and exhibit differences in life history traits, in particular in their...
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