Pooled, Long-read Sequencing for Structural Variant Characterization in Schistosome Populations.

Abstract excerpt

Pooled sequencing provides a rapid cost-effective approach to assess genetic variation segregating within populations of organisms. However, such studies are typically limited to single nucleotide variants and small indels (≤50 bp), and have not been used for structural variants (SVs > 50 bp) which impact large portions of most genomes and may significantly impact phenotype. Here, we examined SVs circulating in...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Genetic Variation
• Share to Genome, Helminth
• Share to Genomic Structural Variation