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Article

Hyperdiverse gene cluster in snail host conveys resistance to human schistosome parasites.

PLoS genetics - 1 Mar 2015

Tennessen Jacob A, Théron André, Marine Melanie, Yeh Jan-Ying, Rognon Anne, Blouin Michael S

Abstract excerpt

Schistosomiasis, a neglected global pandemic, may be curtailed by blocking transmission of the parasite via its intermediate hosts, aquatic snails. Elucidating the genetic basis of snail-schistosome interaction is a key to this strategy. Here we map a natural parasite-resistance polymorphism from a Caribbean population of the snail Biomphalaria glabrata. In independent experimental evolution lines, RAD genotyping...

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Identifiers

PMID: 25775214
DOI: 10.1371/journal.pgen.1005067
PMCID: PMC4361660

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Source receipt: pubmed, retrieved 7 Sept 2026.

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