Role of VAMP3 and VAMP7 in the commitment of<i>Yersinia pseudotuberculosis</i>to LC3-associated pathways involving single- or double-membrane vacuoles

Abstract excerpt

Yersinia pseudotuberculosis can replicate inside macrophages by hijacking autophagy and blocking autophagosome acidification. In bone marrow-derived macrophages, the bacteria are mainly observed inside double-membrane vacuoles positive for LC3, a hallmark of autophagy. Here, we address the question of the membrane traffic during internalization of Yersinia investigating the role of vesicle- associated membrane...

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