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Endocytic SNAREs are involved in optimalCoxiella burnetiivacuole development

6 Dec 2012

Abstract excerpt

Coxiella burnetii is a Gram-negative intracellular bacterium. As previously described, both the endocytic and the autophagic pathways contribute to the maturation of Coxiella replicative vacuoles (CRVs). The large CRVs share the properties of both phagolysosomal and autophagolysosomal compartments. Vamp3, Vamp7 and Vamp8 are v-SNAREs involved in the endocytic pathway which participate mainly in the fusion between...

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PMID: 23217169
DOI: 10.1111/cmi.12087

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