Pathogen-induced formation of a nascent organelle derived from mitochondria

Abstract excerpt

Intracellular pathogens extensively remodel host cells to create environments that support their survival and replication. How pathogens manipulate host organelle biology to promote infection remains a central question in microbial pathogenesis. Here we show that the human parasite Toxoplasma gondii induces the biogenesis of acidified compartments derived from host mitochondria that promote parasite growth. Follo...

Topics

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• Autophagy in Disease and Therapy
• Calcium signaling and nucleotide metabolism
• Inflammasome and immune disorders
• Legionella and Acanthamoeba research
• Mitochondrial Function and Pathology
• Research on Leishmaniasis Studies
• Toxoplasma gondii Research Studies
• Trypanosoma species research and implications

Identifiers and source

Literature Corpus work

6c11cb23-eb4f-548a-9638-08cdcc1605b1

DOI

10.64898/2026.04.23.720395