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Article

Manipulation of Host Cell Organelles by Intracellular Pathogens

12 Apr 2019

Abstract excerpt

ABSTRACT In this article, we explore the unique adaptations of intracellular bacterial pathogens that manipulate conserved cellular pathways, organelles, and cargo to convert the phagosome into a pathogen-containing vacuole (PCV). The phagosome is a degradative organelle that rapidly acidifies as it delivers cargo to the lysosome to destroy microbes and cellular debris. However, to avoid this fate, intracellular...

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PMID: 31025623
DOI: 10.1128/microbiolspec.bai-0022-2019

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