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[18F]VUIIS1009B Features a Superior Imaging Performance to [18F]DPA-714 in TSPO Density Characterization for Neuroinflammatory PET Imaging

2020-09-11

Abstract excerpt

<title>Abstract</title> <p><bold>Purpose:</bold> Translocator protein (TSPO), an outer mitochondrial membrane protein, is regarded as a key biomarker for neuroinflammation in a variety of neurodegenerative diseases. In this study, we aim to evaluate two highly specific TSPO radiotracers [<sup>18</sup>F]VUIIS1009A and [<sup>18</sup>F]VUIIS1009B in a mild cerebral ischemic rat model, and to compare their <italic>in...

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Literature Corpus work
958182c8-4b1a-5b17-a312-586ae0b9468a
DOI
10.21203/rs.3.rs-39569/v2
Open publication

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