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Article

Microglial activation in Parkinson's disease using [18F]-FEPPA.

Journal of neuroinflammation - 11 Jan 2017

Ghadery Christine, Koshimori Yuko, Coakeley Sarah, Harris Madeleine, Rusjan Pablo, Kim Jinhee, Houle Sylvain, Strafella Antonio P

Abstract excerpt

BACKGROUND: Neuroinflammatory processes including activated microglia have been reported to play an important role in Parkinson's disease (PD). Increased expression of translocator protein (TSPO) has been observed after brain injury and inflammation in neurodegenerative diseases. Positron emission tomography (PET) radioligand targeting TSPO allows for the quantification of neuroinflammation in vivo. METHODS:...

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Source

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Identifiers

PMID: 28086916
DOI: 10.1186/s12974-016-0778-1
PMCID: PMC5234135

Genes

TSPO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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