Article

A novel blood-free analytical framework for the quantification of neuroinflammatory load from TSPO PET Imaging

2025-02-03

Abstract excerpt

<title>Abstract</title> <p>Positron Emission Tomography (PET) of the 18 kDa translocator protein (TSPO) is critical for neuroinflammation studies but faces substantial methodological challenges. These include issues with arterial blood sampling for kinetic modeling, the absence of suitable reference regions, genetic polymorphisms affecting tracer affinity, altered blood-to-brain tracer delivery in inflammatory co...

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Literature Corpus work: b2610ce1-1ed0-5887-bdae-6abc7e42d98e
DOI: 10.21203/rs.3.rs-5924801/v1

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