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Article

Feasibility study of TSPO quantification with [18F]FEPPA using population-based input function.

PloS one - 1 Jan 2017

Mabrouk Rostom, Strafella Antonio P, Knezevic Dunja, Ghadery Christine, Mizrahi Romina, Gharehgazlou Avideh, Koshimori Yuko, Houle Sylvain, Rusjan Pablo

Abstract excerpt

PURPOSE: The input function (IF) is a core element in the quantification of Translocator protein 18 kDa with positron emission tomography (PET), as no suitable reference region with negligible binding has been identified. Arterial blood sampling is indeed needed to create the IF (ASIF). In the present manuscript we study individualization of a population based input function (PBIF) with a single arterial manual...

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Source

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Identifiers

PMID: 28545084
DOI: 10.1371/journal.pone.0177785
PMCID: PMC5435246

Genes

TSPO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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