Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Autoimmune diseases association study with the KIAA1109-IL2-IL21 region in a Tunisian population.

Molecular biology reports - 1 Nov 2014

Bouzid Dorra, Fourati Hajer, Amouri Ali, Marques Isabel, Abida Olfa, Tahri Nabil, Penha-Gonçalves Carlos, Masmoudi Hatem

Abstract excerpt

Autoimmune diseases (ADs) share several genetic factors resulting in similarity of disease mechanisms. For instance polymorphisms from the KIAA1109-interleukin 2 (IL2)-IL21 block in the 4q27 chromosome, has been associated with a number of autoimmune phenotypes. Here we performed a haplotype-based analysis of this AD related region in Tunisian patients. Ten single nucleotide polymorphisms (rs6534347, rs11575812,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Autoimmune Diseases
Share to Chromosomes, Human, Pair 4
Share to Genome-Wide Association Study
Share to Haplotypes
Share to Interleukin-2
Share to Linkage Disequilibrium
Share to Proteins
Share to Tunisia

Source

Identifiers

PMID: 25037274
DOI: 10.1007/s11033-014-3596-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Autoimmune diseases association study with the KIAA1109-IL2-IL21 region in a Tunisian population.PMID 25037274Read ↗

Novel genetic risk markers for ulcerative colitis in the IL2/IL21 region are in epistasis with IL23R and suggest a common genetic background for ulcerative colitis and celiac disease.Semantic proximity Read ↗

Novel association in chromosome 4q27 region with rheumatoid arthritis and confirmation of type 1 diabetes point to a general risk locus for autoimmune diseases.Semantic proximity Read ↗

A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21.Semantic proximity Read ↗

Haplotype-based analysis of ulcerative colitis risk loci identifies both IL2 and IL21 as susceptibility genes in Han Chinese.Semantic proximity Read ↗

Association of rs6822844 within the KIAA1109/TENR/IL2/IL21 locus with rheumatoid arthritis in the Algerian population.Semantic proximity Read ↗

Association of ZAP70 and PTPN6, but Not BANK1 or CLEC2D, with inflammatory bowel disease in the Tunisian population.Semantic proximity Read ↗

Evidence for linkage and association between autoimmune thyroid diseases and the 18q12-q21 region in a large Tunisian family.Semantic proximity Read ↗

Polymorphisms in the IL2RA and IL2RB genes in inflammatory bowel disease risk.Semantic proximity Read ↗

Association of IL-23R (rs11209026 A/G) polymorphism with susceptibility to common autoimmune diseases: a meta-analysis combined with trial sequence analysisSemantic proximity Read ↗

Association of KIF21B genetic polymorphisms with ankylosing spondylitis in a Chinese Han population of Shandong Province.Semantic proximity Read ↗

Confirmation of an association between rs6822844 at the Il2-Il21 region and multiple autoimmune diseases: evidence of a general susceptibility locus.Semantic proximity Read ↗

Meta-analysis of two Chinese populations identifies an autoimmune disease risk allele in 22q11.21 as associated with systemic lupus erythematosus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.