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Polymorphisms in the IL2RA and IL2RB genes in inflammatory bowel disease risk.

Genetic testing and molecular biomarkers - 1 Nov 2013

Bouzid Dorra, Amouri Ali, Fourati Hajer, Marques Isabel, Abida Olfa, Tahri Nabil, Goncalves Carlos Penha, Masmoudi Hatem

Abstract excerpt

Associations with different autoimmune diseases of polymorphisms in genes encoding the IL2RA and IL2RB subunits (located in 10p15 and 22q13, respectively), were identified through genome-wide studies. Polymorphisms in these two genes were studied in 107 inflammatory bowel disease (IBD) patients (39 Crohn's disease [CD] and 68 ulcerative colitis [UC]) and in 162 ethnically healthy controls from Tunisia (Sfax). Two...

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Identifiers

PMID: 23972291
DOI: 10.1089/gtmb.2013.0291

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