Article
Evidence for linkage and association between autoimmune thyroid diseases and the 18q12-q21 region in a large Tunisian family.
International journal of immunogenetics - 1 Feb 2006
Hadj Kacem H, Rebai A, Kaffel N, Abid M, Ayadi H
Abstract excerpt
Many studies have shown linkage between IDDM6 locus on 18q12-q21 chromosome and several autoimmune diseases, suggesting that it might harbour susceptibility genes common to autoimmunity. Using 12 families deriving from a large Tunisian multiplex family (the Akr family) from which 38 people were affected with autoimmune thyroid diseases (AITD), and 193 unrelated AITD patients, tested against 100 healthy subjects,...
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