Article
Association of KIF21B genetic polymorphisms with ankylosing spondylitis in a Chinese Han population of Shandong Province.
Clinical rheumatology - 1 Oct 2015
Yang Xinglin, Li Ming, Wang Liya, Hu Zhongdan, Zhang Yuanchao, Yang Qingrui
Abstract excerpt
Previous studies have found that the kinesin family member (KIF) 21B may contribute to the autoimmune disease process. It has been reported that the KIF21B gene is relevant to the pathogenesis of Crohn's disease (CD) and ulcerative colitis (UC). We hypothesized that KIF21B might be a key gene for ankylosing spondylitis (AS) development. To test this hypothesis, 11 tag single nucleotide polymorphisms (SNPs)...
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