Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Haplotype-based analysis of ulcerative colitis risk loci identifies both IL2 and IL21 as susceptibility genes in Han Chinese.

Inflammatory bowel diseases - 1 Dec 2011

Shi Jihua, Zhou Lu, Zhernakova Alexandra, Qian Jiaming, Zhu Feng, Sun Gang, Zhu Liming, Ma Xuejun, Dijkstra Gerard, Wijmenga Cisca, Faber Klaas Nico, Lu Xinghua, Weersma Rinse K

Abstract excerpt

BACKGROUND: The incidence of ulcerative colitis (UC) varies between Western and Eastern ethnicities. A distinct genetic background may play a role in the differences. Until now, very little was known of the UC genetics in Asian populations. Here we performed a haplotype-based analysis of six known UC susceptibility loci in Han Chinese patients. METHODS: In all, 245 UC patients and 300 healthy controls of Han...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colitis, Ulcerative

Share to Haplotypes

Share to Interleukin-2

Share to Interleukin-21

Share to Interleukins

Share to Linkage Disequilibrium

Source

Identifiers

PMID: 21648020
DOI: 10.1002/ibd.21652

Genes

ECM1
MST1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Haplotype-based analysis of ulcerative colitis risk loci identifies both IL2 and IL21 as susceptibility genes in Han Chinese.PMID 21648020Read ↗

Novel genetic risk markers for ulcerative colitis in the IL2/IL21 region are in epistasis with IL23R and suggest a common genetic background for ulcerative colitis and celiac disease.Semantic proximity Read ↗

Genetic variants in the region harbouring IL2/IL21 associated with ulcerative colitis.Semantic proximity Read ↗

Identification of Ten Additional Susceptibility Loci for Ulcerative Colitis Through Immunochip Analysis in Koreans.Semantic proximity Read ↗

Replication study of ulcerative colitis risk loci in a Lithuanian-Latvian case-control sample.Semantic proximity Read ↗

A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21.Semantic proximity Read ↗

Autoimmune diseases association study with the KIAA1109-IL2-IL21 region in a Tunisian population.Semantic proximity Read ↗

Genetic Analysis of Ulcerative Colitis in Japanese Individuals Using Population-specific SNP Array.Semantic proximity Read ↗

Analysis of IL2/IL21 gene variants in cholestatic liver diseases reveals an association with primary sclerosing cholangitis.Semantic proximity Read ↗

Association of the interleukin-22 genetic polymorphisms with ulcerative colitis.Semantic proximity Read ↗

Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility.Semantic proximity Read ↗

Association of single nucleotide polymorphisms of IL23R and IL17 with ulcerative colitis risk in a Chinese Han population.Semantic proximity Read ↗

Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.