Article
Association of ZAP70 and PTPN6, but Not BANK1 or CLEC2D, with inflammatory bowel disease in the Tunisian population.
Genetic testing and molecular biomarkers - 1 Apr 2013
Bouzid Dorra, Fourati Hajer, Amouri Ali, Marques Isabel, Abida Olfa, Haddouk Samy, Ben Ayed Mourad, Tahri Nabil, Penha-Gonçalves Carlos, Masmoudi Hatem
Abstract excerpt
Inflammatory bowel diseases (IBDs), consisting of ulcerative colitis (UC) and Crohn's disease (CD), are complex disorders with multiple genes contributing to disease pathogenesis. We aimed to identify the associations of genetic variations in the ZAP70, PTPN6, BANK1, and CLEC2D genes encoding for intracellular signaling molecules with IBDs. One hundred seven patients (39 CD and 68 UC) with IBD and 162 healthy...
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