Article
Stepwise threshold clustering: a new method for genotyping MHC loci using next-generation sequencing technology.
PloS one - 1 Jan 2014
Stutz William E, Bolnick Daniel I
Abstract excerpt
Genes of the vertebrate major histocompatibility complex (MHC) are of great interest to biologists because of their important role in immunity and disease, and their extremely high levels of genetic diversity. Next generation sequencing (NGS) technologies are quickly becoming the method of choice for high-throughput genotyping of multi-locus templates like MHC in non-model organisms. Previous approaches to...
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