Article
MHCtools - an R package for MHC high-throughput sequencing data: Genotyping, haplotype and supertype inference, and downstream genetic analyses in non-model organisms.
Molecular ecology resources - 1 Oct 2022
Roved Jacob, Hansson Bengt, Stervander Martin, Hasselquist Dennis, Westerdahl Helena
Abstract excerpt
The major histocompatibility complex (MHC) plays a central role in the vertebrate adaptive immune system and has been of long-term interest in evolutionary biology. While several protocols have been developed for MHC genotyping, there is a lack of transparent and standardized tools for downstream analysis of MHC data. Here, we present the r package mhctools and demonstrate the use of its functions to (i) assist...
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