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Article

454 screening of individual MHC variation in an endemic island passerine.

Immunogenetics - 1 Mar 2015

Gonzalez-Quevedo Catalina, Phillips Karl P, Spurgin Lewis G, Richardson David S

Abstract excerpt

Genes of the major histocompatibility complex (MHC) code for receptors that are central to the adaptive immune response of vertebrates. These genes are therefore important genetic markers with which to study adaptive genetic variation in the wild. Next-generation sequencing (NGS) has increasingly been used in the last decade to genotype the MHC. However, NGS methods are highly prone to sequencing errors, and...

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Animal Distribution
Exons
Gene Conversion
Genes, MHC Class I
Genetic Speciation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Selection, Genetic

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PMID: 25515684
DOI: 10.1007/s00251-014-0822-1
PMCID: PMC4325181

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