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Article

MHC genotyping of non-model organisms using next-generation sequencing: a new methodology to deal with artefacts and allelic dropout.

BMC genomics - 9 Aug 2013

Sommer Simone, Courtiol Alexandre, Mazzoni Camila J

Abstract excerpt

BACKGROUND: The Major Histocompatibility Complex (MHC) is the most important genetic marker to study patterns of adaptive genetic variation determining pathogen resistance and associated life history decisions. It is used in many different research fields ranging from human medical, molecular evolutionary to functional biodiversity studies. Correct assessment of the individual allelic diversity pattern and the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23937623
DOI: 10.1186/1471-2164-14-542
PMCID: PMC3750822

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