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Article

Improved high-throughput MHC typing for non-model species using long-read sequencing.

Molecular ecology resources - 1 Apr 2022

Cheng Yuanyuan, Grueber Catherine, Hogg Carolyn J, Belov Katherine

Abstract excerpt

The major histocompatibility complex (MHC) plays a critical role in the vertebrate immune system. Accurate MHC typing is critical to understanding not only host fitness and disease susceptibility, but also the mechanisms underlying host-pathogen co-evolution. However, due to the high degree of gene duplication and diversification of MHC genes, it is often technically challenging to accurately characterise MHC...

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Identifiers

PMID: 34551192
DOI: 10.1111/1755-0998.13511
PMCID: PMC9293008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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