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[Association between methylene-tetrahydrofolate reductase gene polymorphisms and chronic myeloid leukemia].

Bulletin du cancer - 1 Sept 2014

Dorgham Samia, Aberkane Meriem, Boughrara Wefa, Antar Soltan Badra, Mehalhal Nemra, Touhami Hadj, Sidimansour Noureddine, Merad Boudia Nadia, Louhibi Lotfi, Boudjema Abdallah

Abstract excerpt

Methylene-tetrahydrofolate reductase (MTHFR) is a key enzyme of folate metabolism. Few studies were reported about its relationship with chronic myeloid leukemia (CML). We conducted a case-control study analyzing the prevalence of the polymorphisms MTHFR C677T and MTHFR A1298C in Algerians CML patients. Using TaqMan(®) allelic discrimination assay, we investigate MTHFR C677T and A1298C polymorphism distribution...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Leukemia, Myelogenous, Chronic, BCR-ABL Positive

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Share to Polymorphism, Genetic

Source

Identifiers

PMID: 25036376
DOI: 10.1684/bdc.2014.1953

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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