Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MTHFR genetic polymorphisms may contribute to the risk of chronic myelogenous leukemia in adults: a meta-analysis of 12 genetic association studies.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 May 2014

Li Bin, Zhang Jian, Wang Lei, Li Yan, Jin Juping, Ai Limei, Li Chong, Li Zhe, Mao Shudan

Abstract excerpt

Chronic myelogenous leukemia (CML) is a complex disease with a genetic basis. The genetic association studies (GASs) that have investigated the association between adult CML and 5,10-methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms have produced contradictory and inconclusive results. The aim of this meta-analysis is to provide a relatively comprehensive assessment of the association of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to MTHFR gene
Share to Genetic Association Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Leukemia, Myelogenous, Chronic, BCR-ABL Positive

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 24379141
DOI: 10.1007/s13277-013-1554-9

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MTHFR genetic polymorphisms may contribute to the risk of chronic myelogenous leukemia in adults: a meta-analysis of 12 genetic association studies.PMID 24379141Read ↗

Methylenetetrahydrofolate reductase gene polymorphism and risk of chronic myelogenous leukemia: a meta-analysis.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase gene polymorphisms contribute to acute myeloid leukemia and chronic myeloid leukemia susceptibilities: evidence from meta-analyses.Semantic proximity Read ↗

Update meta-analysis from biomedical literature about MTHFR'polymorphisms and the CML' risk.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase A1298C genotypes are associated with the risks of acute lymphoblastic leukaemia and chronic myelogenous leukaemia in the Korean populationSemantic proximity Read ↗

Methylene tetrahydrofolate reductase (MTHFR) gene polymorphisms in chronic myeloid leukemia: an Egyptian study.Semantic proximity Read ↗

MTHFR gene polymorphism and risk of myeloid leukemia: a meta-analysis.Semantic proximity Read ↗

Association between MTHFR polymorphisms and acute myeloid leukemia risk: a meta-analysis.Semantic proximity Read ↗

MTHFR 677CC/1298CC genotypes are highly associated with chronic myelogenous leukemia: a case-control study in Korea.Semantic proximity Read ↗

MTHFR A1298C and C677T gene polymorphisms and susceptibility to chronic myeloid leukemia in Egypt.Semantic proximity Read ↗

The methylenetetrahydrofolate reductase (MTHFR) 677 C>T polymorphism increases the risk of developing chronic myeloid leukemia-a case-control study.Semantic proximity Read ↗

Association of the 5,10-methylenetetrahydrofolate reductase (MTHFR C677T and A1298C) polymorphisms in Korean patients with adult acute lymphoblastic leukemia.Semantic proximity Read ↗

Association between methylenetetrahydrofolate reductase polymorphism C677T and risk of chronic myeloid leukemia in Serbian population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.