Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MTHFR A1298C and C677T gene polymorphisms and susceptibility to chronic myeloid leukemia in Egypt.

International journal of clinical and experimental pathology - 1 Jan 2014

Aly Rabab M, Taalab Mona M, Ghazy Hayam F

Abstract excerpt

Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme regulating the intracellular folate metabolism which plays an important role in carcinogenesis through DNA methylation. We aimed to evaluate the association between MTHFR A1298C and C677T polymorphisms and the risks of chronic myeloid leukemia (CML). Eighty-five patients with CML and a control group containing 100 healthy, age and sex matched individuals...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chi-Square Distribution
Share to Drug Resistance, Neoplasm

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Kaplan-Meier Estimate

Share to Leukemia, Myelogenous, Chronic, BCR-ABL Positive

Share to Logistic Models

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Odds Ratio

Source

Open in PubMed Open full text

Identifiers

PMID: 24966971
PMCID: PMC4069873

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MTHFR A1298C and C677T gene polymorphisms and susceptibility to chronic myeloid leukemia in Egypt.PMID 24966971Read ↗

Methylene tetrahydrofolate reductase (MTHFR) gene polymorphisms in chronic myeloid leukemia: an Egyptian study.Semantic proximity Read ↗

The methylenetetrahydrofolate reductase (MTHFR) 677 C>T polymorphism increases the risk of developing chronic myeloid leukemia-a case-control study.Semantic proximity Read ↗

MTHFR 677CC/1298CC genotypes are highly associated with chronic myelogenous leukemia: a case-control study in Korea.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase gene polymorphisms contribute to acute myeloid leukemia and chronic myeloid leukemia susceptibilities: evidence from meta-analyses.Semantic proximity Read ↗

[Association between methylene-tetrahydrofolate reductase gene polymorphisms and chronic myeloid leukemia].Semantic proximity Read ↗

Methylenetetrahydrofolate Reductase Gene Polymorphisms and Risk of Myeloid Leukemia: Table 1Semantic proximity Read ↗

Association between methylenetetrahydrofolate reductase polymorphism C677T and risk of chronic myeloid leukemia in Serbian population.Semantic proximity Read ↗

MTHFR genetic polymorphisms may contribute to the risk of chronic myelogenous leukemia in adults: a meta-analysis of 12 genetic association studies.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase gene polymorphism and risk of chronic myelogenous leukemia: a meta-analysis.Semantic proximity Read ↗

Update meta-analysis from biomedical literature about MTHFR'polymorphisms and the CML' risk.Semantic proximity Read ↗

Association between the MTHFR A1298C polymorphism and increased risk of acute myeloid leukemia in Brazilian children.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase A1298C genotypes are associated with the risks of acute lymphoblastic leukaemia and chronic myelogenous leukaemia in the Korean populationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.