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Article

Methylenetetrahydrofolate reductase gene polymorphism and risk of chronic myelogenous leukemia: a meta-analysis.

Journal of B.U.ON. : official journal of the Balkan Union of Oncology - 1 Jan 2000

Li Chen, Yichao Jin, Jiaxin Lin, Yueting Zhang, Qin Lu, Tonghua Yang

Abstract excerpt

PURPOSE: Reported evidence supports a role for methylenetetrahydrofolate reductase (MTHFR) in the risk of chronic myelogenous leykemia (CML). However, these reports arrived at non-conclusive and even conflicting results regarding the association between two common MTHFR polymorphisms (C677T and A1298C) and CML risk. Thus, a meta-analysis was carried out to clarify a more precise association between these two...

Topics

Asian People
Genetic Predisposition to Disease
Humans
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Methylenetetrahydrofolate Reductase (NADPH2)
Polymorphism, Genetic
Publication Bias
Risk
White People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26854451

Genes

MTHFR

Variants

Provenance

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Methylenetetrahydrofolate reductase gene polymorphism and risk of chronic myelogenous leukemia: a meta-analysis.PMID 26854451Read ↗

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