Article
Methylenetetrahydrofolate reductase gene polymorphism and risk of chronic myelogenous leukemia: a meta-analysis.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology - 1 Jan 2000
Li Chen, Yichao Jin, Jiaxin Lin, Yueting Zhang, Qin Lu, Tonghua Yang
Abstract excerpt
PURPOSE: Reported evidence supports a role for methylenetetrahydrofolate reductase (MTHFR) in the risk of chronic myelogenous leykemia (CML). However, these reports arrived at non-conclusive and even conflicting results regarding the association between two common MTHFR polymorphisms (C677T and A1298C) and CML risk. Thus, a meta-analysis was carried out to clarify a more precise association between these two...
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