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Article

MTHFR 677CC/1298CC genotypes are highly associated with chronic myelogenous leukemia: a case-control study in Korea.

Leukemia research - 1 Sept 2007

Moon Hee Won, Kim Tae Young, Oh Bo Ra, Min Hyun Chung, Cho Han Ik, Bang Soo Mee, Lee Jae Hoon, Yoon Sung Soo, Lee Dong Soon

Abstract excerpt

Methylenetetrahydrofolate reductase (MTHFR) is an enzyme involved in folate metabolism and DNA methylation. Studies on MTHFR polymorphism in leukemia have largely focused on the protective role of MTHFR polymorphism in acute lymphoblastic leukemia (ALL). We evaluated the C677T and A1298C polymorphisms using the TaqMan allelic discrimination assay in various malignancies. The study population included 115 subjects...

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Source

Identifiers

PMID: 17156840
DOI: 10.1016/j.leukres.2006.10.016

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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MTHFR 677CC/1298CC genotypes are highly associated with chronic myelogenous leukemia: a case-control study in Korea.PMID 17156840Read ↗

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