Article
Multimotor transport in a system of active and inactive kinesin-1 motors.
Biophysical journal - 15 Jul 2014
Scharrel Lara, Ma Rui, Schneider René, Jülicher Frank, Diez Stefan
Abstract excerpt
Long-range directional transport in cells is facilitated by microtubule-based motor proteins. One example is transport in a nerve cell, where small groups of motor proteins, such as kinesins and cytoplasmic dynein, work together to ensure the supply and clearance of cellular material along the axon. Defects in axonal transport have been linked to Alzheimer's and other neurodegenerative diseases. However, it is...
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