Article
Kinesin-1 and Dynein are the primary motors for fast transport of mitochondria in Drosophila motor axons.
Molecular biology of the cell - 1 Apr 2006
Pilling Aaron D, Horiuchi Dai, Lively Curtis M, Saxton William M
Abstract excerpt
To address questions about mechanisms of filament-based organelle transport, a system was developed to image and track mitochondria in an intact Drosophila nervous system. Mutant analyses suggest that the primary motors for mitochondrial movement in larval motor axons are kinesin-1 (anterograde) and cytoplasmic dynein (retrograde), and interestingly that kinesin-1 is critical for retrograde transport by dynein....
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