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Article

Tug-of-war as a cooperative mechanism for bidirectional cargo transport by molecular motors.

Proceedings of the National Academy of Sciences of the United States of America - 25 Mar 2008

Müller Melanie J I, Klumpp Stefan, Lipowsky Reinhard

Abstract excerpt

Intracellular transport is based on molecular motors that pull cargos along cytoskeletal filaments. One motor species always moves in one direction, e.g., conventional kinesin moves to the microtubule plus end, whereas cytoplasmic dynein moves to the microtubule minus end. However, many cellular...

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Identifiers

PMID: 18347340
DOI: 10.1073/pnas.0706825105
PMCID: PMC2290779

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18347340-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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