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Article

Blood DNA methylation, nevi number, and the risk of melanoma.

Melanoma research - 1 Oct 2014

Pergoli Laura, Favero Chiara, Pfeiffer Ruth M, Tarantini Letizia, Calista Donato, Cavalleri Tommaso, Angelici Laura, Consonni Dario, Bertazzi Pier A, Pesatori Angela C, Landi Maria T, Bollati Valentina

Abstract excerpt

Germline mutations determining increased cutaneous malignant melanoma (CMM) risk have been identified in familial and sporadic CMM cases, but they account only for a small proportion of CMM cases. Recent evidence suggests that germline epimutations (e.g. DNA methylation alterations), which can be inherited similarly to genomic mutations and can be detected in normal body cells (including blood), might increase...

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Identifiers

PMID: 25026000
DOI: 10.1097/CMR.0000000000000112
PMCID: PMC6857929

Genes

CDK4
MLH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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