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Article

Influence of germline genetic variants on dermoscopic features of melanoma.

Pigment cell & melanoma research - 1 May 2021

Pozzobon Flavia Carolina, Tell-Marti Gemma, Calbet-Llopart Neus, Barreiro Alicia, Espinosa Natalia, Potrony Míriam, Alejo Beatriz, Podlipnik Sebastian, Combalia Marc, Puig-Butillé Joan Anton, Carrera Cristina, Malvehy Josep, Puig Susana

Abstract excerpt

Nevus count is highly determined by inherited variants and has been associated with the origin of melanoma. De novo melanomas (DNMMs) are more prevalent in patients with a low nevus count and have distinctive dermoscopic features than nevus-associated melanomas. We evaluated the impact of nine single nucleotide polymorphisms (SNPs) of MTAP (rs10811629, rs2218220, rs7023329 and rs751173), PLA2G6 (rs132985 and...

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Share to Biomarkers, Tumor
Share to Hair Color
Share to Melanoma
Share to Nevus, Pigmented
Share to Polymorphism, Single Nucleotide
Share to Receptor, Melanocortin, Type 1
Share to Skin Neoplasms

Source

Identifiers

PMID: 33342058
DOI: 10.1111/pcmr.12954

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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