Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene mutation patterns in patients with minimally differentiated acute myeloid leukemia.

Neoplasia (New York, N.Y.) - 1 Jun 2014

Kao Hsiao-Wen, Liang Der-Cherng, Wu Jin-Hou, Kuo Ming-Chung, Wang Po-Nan, Yang Chao-Ping, Shih Yu-Shu, Lin Tung-Huei, Huang Yu-Hui, Shih Lee-Yung

Abstract excerpt

Minimally differentiated acute myeloid leukemia (AML-M0) is a rare subtype of AML with poor prognosis. Although genetic alterations are increasingly reported in AML, the gene mutations have not been comprehensively studied in AML-M0. We aimed to examine a wide spectrum of gene mutations in patients with AML-M0 to determine their clinical relevance. Twenty gene mutations including class I, class II, class III of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Aberrations
Share to Gene Regulatory Networks

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Infant

Share to Karyotype

Share to Leukemia, Myeloid, Acute

Share to Mutation Rate

Share to Neoplasm Grading

Share to Patient Outcome Assessment

Source

Open in PubMed Open full text

Identifiers

PMID: 25022553
DOI: 10.1016/j.neo.2014.06.002
PMCID: PMC4198802

Genes

FLT3
RUNX1
ASXL1
IDH1
IDH2
TET2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene mutation patterns in patients with minimally differentiated acute myeloid leukemia.PMID 25022553Read ↗

Clinical and Biological Implications of Mutational Spectrum in Acute Myeloid Leukemia of FAB Subtypes M0 and M1.Semantic proximity Read ↗

Gene expression profiling of minimally differentiated acute myeloid leukemia: M0 is a distinct entity subdivided by RUNX1 mutation status.Semantic proximity Read ↗

Genetic alteration patterns and clinical outcomes of elderly and secondary acute myeloid leukemia.Semantic proximity Read ↗

Gene mutation patterns and their prognostic impact in a cohort of 1185 patients with acute myeloid leukemiaSemantic proximity Read ↗

Multi-omics analysis of pediatric minimally differentiated acute myeloid leukemia reveals RUNX1-driven stemness and chemoresistance.Semantic proximity Read ↗

Mutations in epigenetic modifiers in acute myeloid leukemia and their clinical utility.Semantic proximity Read ↗

Current findings for recurring mutations in acute myeloid leukemia.Semantic proximity Read ↗

High frequency of additional gene mutations in acute myeloid leukemia with MLL partial tandem duplication: DNMT3A mutation is associated with poor prognosis.Semantic proximity Read ↗

Comprehensive analysis of genetic alterations and their prognostic impacts in adult acute myeloid leukemia patients.Semantic proximity Read ↗

Subtype-specific patterns of molecular mutations in acute myeloid leukemia.Semantic proximity Read ↗

Mutational spectrum and prognostic stratification of intermediate-risk acute myeloid leukemia.Semantic proximity Read ↗

Gene mutation and AML pathogenesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.