Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic alteration patterns and clinical outcomes of elderly and secondary acute myeloid leukemia.

Hematological oncology - 1 Oct 2019

Wang Shi-Yang, Cheng Wen-Yan, Mao Yuan-Fei, Zhu Yong-Mei, Liu Fu-Jia, Ma Ting-Ting, Shen Yang

Abstract excerpt

To illustrate the clinical and genetic features of elderly and secondary acute myeloid leukemia (AML) patients, we compared 145 elderly AML (e-AML) and 55 secondary AML (s-AML) patients with 451 young de novo AML patients. Both e-AML and s-AML patients showed lower white blood cell (WBC) and bone marrow (BM) blasts at diagnosis. NPM1, DNMT3A, and IDH2 mutations were more common while biallelic CEBPA and IDH1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genes, Neoplasm
Share to Leukocyte Count

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasm, Residual

Share to Neoplasms, Second Primary

Share to Neoplastic Stem Cells

Share to Nucleophosmin

Share to Progression-Free Survival

Share to Remission Induction

Source

Open in PubMed Open full text

Identifiers

PMID: 31348835
DOI: 10.1002/hon.2656
PMCID: PMC6899678

Genes

EFS
DNMT3A
IDH1
IDH2
KMT2A
NPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic alteration patterns and clinical outcomes of elderly and secondary acute myeloid leukemia.PMID 31348835Read ↗

[Molecular Features and Clinical Significance of Acute Myeloid Leukemia in Elderly Patients].Semantic proximity Read ↗

Genetic features and efficacy of decitabine-based chemotherapy in elderly patients with acute myeloid leukemia.Semantic proximity Read ↗

Genomic mutation patterns and prognostic value in de novo and secondary acute myeloid leukemia: A multicenter study from China.Semantic proximity Read ↗

[Comparision of Mutational Spectrum between Elderly and Young Adults with Acute Myeloid Leukemia Based on Next Generation Sequencing].Semantic proximity Read ↗

Genetic and Genomic Landscape of Secondary and Therapy-Related Acute Myeloid Leukemia.Semantic proximity Read ↗

Genetic Abnormalities and Challenges in the Treatment of Acute Myeloid LeukemiaSemantic proximity Read ↗

Aging and comprehensive molecular profiling in acute myeloid leukemia.Semantic proximity Read ↗

Age-dependent clinical, molecular, and prognostic differences in patients with AML: a retrospective study.Semantic proximity Read ↗

Recent Advances Towards the Understanding of Secondary Acute Myeloid Leukemia ProgressionSemantic proximity Read ↗

[Prognostic significance of different IDH mutations and accompanying gene mutations in patients with acute myeloid leukemia].Semantic proximity Read ↗

Acute myeloid leukemia ontogeny is defined by distinct somatic mutations.Semantic proximity Read ↗

Gene mutation patterns in patients with minimally differentiated acute myeloid leukemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.