Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical and Biological Implications of Mutational Spectrum in Acute Myeloid Leukemia of FAB Subtypes M0 and M1.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 1 Jan 2018

Cheng Zhiheng, Dai Yifeng, Pang Yifan, Jiao Yang, Zhao Hongmian, Wu Sun, Zhang Lingxiu, Zhang Yuan, Wang Xiufeng, Wang Lihua, Ma Dong, Qin Tong, Hu Ning, Zhang Yijie, Hu Kai, Zhang Qingyi, Shi Jinlong, Fu Lin

Abstract excerpt

BACKGROUND/AIMS: Acute myeloid leukemia (AML) of French-American-British (FAB) subtypes M0 and M1 are both poorly differentiated AML, but their mutational spectrum and molecular characteristics remain unknown. This study aimed to explore the mutational spectrum and prognostic factors of AML-M0 and M1. METHODS: Sixty-five AML patients derived from The Cancer Genome Atlas (TCGA) database were enrolled in this...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Databases, Factual

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease-Free Survival

Share to Leukemia, Myeloid, Acute

Share to Neoplasm Proteins

Share to Nucleophosmin

Share to Risk Assessment

Share to Survival Rate

Source

Identifiers

PMID: 29961066
DOI: 10.1159/000491065

Genes

EFS
NPM1
FLT3
IDH1
IDH2
RUNX1
TET2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical and Biological Implications of Mutational Spectrum in Acute Myeloid Leukemia of FAB Subtypes M0 and M1.PMID 29961066Read ↗

Clinical and biological implications of mutational spectrum in acute myeloid leukemia of FAB subtypes M4 and M5.Semantic proximity Read ↗

Molecular and clinical significance of FLT3, NPM1, DNMT3A and TP53 mutations in acute myeloid leukemia patients.Semantic proximity Read ↗

Genomic mutation patterns and prognostic value in de novo and secondary acute myeloid leukemia: A multicenter study from China.Semantic proximity Read ↗

Mutational spectrum and prognostic stratification of intermediate-risk acute myeloid leukemia.Semantic proximity Read ↗

Genomics of Acute Myeloid Leukemia Diagnosis and Pathways.Semantic proximity Read ↗

Clinical Characteristics, Molecular Analysis and Survival Outcomes of Patients With Extramedullary Acute Myeloid Leukemia: A Retrospective Single-Center Study.Semantic proximity Read ↗

Investigations of the prognostic value of RUNX1 mutation in acute myeloid leukemia patients: Data from a real-world study.Semantic proximity Read ↗

Acute myeloid leukaemia genomics.Semantic proximity Read ↗

Additional gene mutations may refine the 2017 European LeukemiaNet classification in adult patients with de novo acute myeloid leukemia aged <60 years.Semantic proximity Read ↗

Cytogenetic abnormalities in NPM1-mutated acute myeloid leukemia.Semantic proximity Read ↗

The characteristics and prognostic analysis of therapy-related acute myeloid leukemia patients in China.Semantic proximity Read ↗

A concise review on the molecular genetics of acute myeloid leukemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.