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Article

Subtype-specific patterns of molecular mutations in acute myeloid leukemia.

Leukemia - 1 Jan 2017

Rose D, Haferlach T, Schnittger S, Perglerová K, Kern W, Haferlach C

Abstract excerpt

Acute myeloid leukemia (AML) can be grouped into morphologically or genetically defined subtypes. Today, the AML phenotype-genotype associations, that is, FAB/WHO (French-American-British/World Health Organization) definitions and recurrent molecular mutations, are not fully understood. Therefore, we evaluated the impact of molecular mutations on the AML differentiation stage by molecular profiling of 4373 adult...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27285584
DOI: 10.1038/leu.2016.163

Genes

NPM1
ASXL1
DNMT3A
RUNX1
FLT3
KRAS
TP53
WT1
IDH1
NRAS
TET2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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