Article
Current findings for recurring mutations in acute myeloid leukemia.
Journal of hematology & oncology - 14 Sept 2011
Takahashi Shinichiro
Abstract excerpt
The development of acute myeloid leukemia (AML) is a multistep process that requires at least two genetic abnormalities for the development of the disease. The identification of genetic mutations in AML has greatly advanced our understanding of leukemogenesis. Recently, the use of novel technologies, such as massively parallel DNA sequencing or high-resolution single-nucleotide polymorphism arrays, has allowed...
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