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Article

Gene expression profiling of minimally differentiated acute myeloid leukemia: M0 is a distinct entity subdivided by RUNX1 mutation status.

Blood - 1 Oct 2009

Silva Fernando P G, Swagemakers Sigrid M A, Erpelinck-Verschueren Claudia, Wouters Bas J, Delwel Ruud, Vrieling Harry, van der Spek Peter, Valk Peter J M, Giphart-Gassler Micheline

Abstract excerpt

Minimally differentiated acute myeloid leukemia (AML-M0) is defined by immature morphology and expression of early hematologic markers. By gene expression profiling (GEP) and subsequent unsupervised analysis of 35 AML-M0 samples and 253 previously reported AML cases, we demonstrate that AML-M0 ca...

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Source

Identifiers

PMID: 19666867
DOI: 10.1182/blood-2009-03-211334

Genes

RUNX1
ETS2
ETV6
MPO
PRDM1
RUNX3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19666867-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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