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Article

Mutational spectrum and prognostic stratification of intermediate-risk acute myeloid leukemia.

Cancer gene therapy - 1 Aug 2018

Wu Sun, Dai Yifeng, Zhang Yuan, Wang Xiufeng, Wang Lihua, Ma Dong, Zhang Lingxiu, Pang Yifan, Jiao Yang, Niu Mingshan, Xu Kailin, Ke Xiaoyan, Shi Jinlong, Cheng Zhiheng, Fu Lin

Abstract excerpt

The mutational spectrum and prognostic stratification of intermediate-risk acute myeloid leukemia (IR-AML), which accounts for a substantial number of AML, are unclear. In order to explore the prognostic significance of the mutational spectrum in IR-AML, 106 IR-AML patients were collected from The Cancer Genome Atlas database. Sixty-two patients underwent chemotherapy-only, forty-four proceeded to allogeneic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29904089
DOI: 10.1038/s41417-018-0028-z

Genes

FLT3
RUNX1
EFS
IDH1
IDH2
NPM1
TET2

Provenance

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