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Article

NT5C3 polymorphisms and outcome of first induction chemotherapy in acute myeloid leukemia.

Pharmacogenetics and genomics - 1 Sept 2014

Cheong Hyun Sub, Koh Youngil, Ahn Kwang-Sung, Lee Chansu, Shin Hyoung Doo, Yoon Sung-Soo

Abstract excerpt

AIMS: The cytosolic 5'-nucleotidase-III (NT5C3) is involved in the metabolism of the nucleoside analog, cytosine arabinose (AraC), and the expression level of NT5C3 is correlated with sensitivity to AraC in acute myeloid leukemia (AML) patients. The current study examined whether the NT5C3 polymorphisms could affect chemotherapy outcomes in 103 Korean AML patients. METHODS: Forty-seven single nucleotide...

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Share to 5'-Nucleotidase
Share to Antimetabolites, Antineoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytarabine

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Share to Leukemia, Myeloid, Acute

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Source

Identifiers

PMID: 25000516
DOI: 10.1097/FPC.0000000000000072

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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