Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

GATA2 rs2335052 and GATA2 rs78245253 single-nucleotide polymorphisms in Chinese patients with acute myelocytic leukemia.

International journal of laboratory hematology - 1 Dec 2021

Fang Fang, Xu Jing, Kang Yefang, Ren Huanying, Muyey Daniel Muteb, Chen Xiuhua, Tan Yanhong, Xu Zhifang, Wang Hongwei

Abstract excerpt

INTRODUCTION: GATA binding protein 2 (GATA2) gene, involved in progression of hematologic malignancies and various solid tumors, is a susceptibility gene for inherited acute myeloid leukemia (AML). However, the influence of its single-nucleotide polymorphisms (SNPs) on AML remains unknown. METHODS: We used allele-specific PCR to genotype GATA2 rs2335052 and rs78245253 in 159 newly diagnosed AML (non-M3) patients...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Alleles
Share to Antineoplastic Combined Chemotherapy Protocols
Share to China
Share to GATA2 Transcription Factor
Share to Genetic Association Studies
Share to Leukemia, Myeloid, Acute
Share to Prognosis
Share to Treatment Outcome

Source

Identifiers

PMID: 34374210
DOI: 10.1111/ijlh.13649

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

GATA2 rs2335052 and GATA2 rs78245253 single-nucleotide polymorphisms in Chinese patients with acute myelocytic leukemia.PMID 34374210Read ↗

GATA-2 L359 V mutation is exclusively associated with CML progression but not other hematological malignancies and GATA-2 P250A is a novel single nucleotide polymorphism.Semantic proximity Read ↗

GATA3 rs3824662 gene polymorphism as possible risk factor in a cohort of Egyptian patients with pediatric acute lymphoblastic leukemia and its prognostic impact.Semantic proximity Read ↗

[Clinical Characteristics and Prognosis of Acute Myeloid Leukemia Patients with GATA2 Gene Mutation].Semantic proximity Read ↗

Prognostic significance of GATA2 in patients with MDS/AML: a systematic review and meta-analysis.Semantic proximity Read ↗

Long non-coding RNA GAS5 polymorphism predicts a poor prognosis of acute myeloid leukemia in Chinese patients via affecting hematopoietic reconstitution.Semantic proximity Read ↗

Cytogenetic and Molecular Genetic Driven Prediction of Response to First-Treatment and Prognosis in Acute Myeloid Leukemia: A Retrospective Cohort Study.Semantic proximity Read ↗

Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.Semantic proximity Read ↗

Acute myeloid leukemia associated with a novel GATA2 mutation: a case report and the importance to identify GATA2 haplodeficiency.Semantic proximity Read ↗

Dual biomarkers long non-coding RNA GAS5 and its target, NR3C1, contribute to acute myeloid leukemia.Semantic proximity Read ↗

GATA2 Mutations Predict Poor Prognosis in Transplanted Myeloid Neoplasms.Semantic proximity Read ↗

Exome Sequencing Identifies Highly Recurrent Somatic GATA2 and CEBPA Mutations in Acute Erythroid LeukemiaSemantic proximity Read ↗

Correlation of TET2 SNP rs2454206 with improved survival in children with acute myeloid leukemia featuring intermediate-risk cytogenetics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.