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Article

SLC29A1 single nucleotide polymorphisms as independent prognostic predictors for survival of patients with acute myeloid leukemia: an in vitro study.

Journal of experimental & clinical cancer research : CR - 15 Nov 2014

Wan Haixia, Zhu Jianyi, Chen Fangyuan, Xiao Fei, Huang Honghui, Han Xiaofeng, Zhong Lu, Zhong Hua, Xu Lan, Ni Beiwen, Zhong Jihua

Abstract excerpt

BACKGROUND: The mechanism behind poor survival of acute myeloid leukemia (AML) patients with 1-barabinofuranosylcytosine (Ara-C) based treatment remains unclear. This study aimed to assess the pharmacogenomic effects of Ara-C metabolic pathway in patients with AML. METHODS: The genotypes of 19 single nucleotide polymorphisms (SNPs) of DCK, CDA and SLC29A1from 100 AML patients treated with Ara-C were examined. All...

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Share to Antimetabolites, Antineoplastic
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25398670
DOI: 10.1186/s13046-014-0090-9
PMCID: PMC4234887

Genes

CDA
DCK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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