Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

WASH complex regulates Arp2/3 complex for actin-based polar body extrusion in mouse oocytes

7 Jul 2014

Abstract excerpt

Prior to their fertilization, oocytes undergo asymmetric division, which is regulated by actin filaments. Recently, WASH complex were identified as actin nucleation promoting factors (NPF) that activated Arp2/3 complex. However, the roles of WASH complex remain uncertain, particularly for oocyte polarization and asymmetric division. Here, we examined the functions of two important subunits of a WASH complex,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cellular Mechanics and Interactions
Share to Microtubule and mitosis dynamics
Share to Reproductive Biology and Fertility

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24998208
DOI: 10.1038/srep05596

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

WASH complex regulates Arp2/3 complex for actin-based polar body extrusion in mouse oocytesPMID 24998208Read ↗

JMY is required for asymmetric division and cytokinesis in mouse oocytesSemantic proximity Read ↗

Aberrant cortex contractions impact mammalian oocyte qualitySemantic proximity Read ↗

Actin-based spindle positioning: new insights from female gametesSemantic proximity Read ↗

Wash functions downstream of Rho and links linear and branched actin nucleation factorsSemantic proximity Read ↗

Actin protects mammalian eggs against chromosome segregation errorsSemantic proximity Read ↗

PAK4 Regulates Actin and Microtubule Dynamics during Meiotic Maturation in Mouse OocyteSemantic proximity Read ↗

Assembly and Positioning of the Oocyte Meiotic SpindleSemantic proximity Read ↗

Actin organizes chromosomes and microtubules to ensure mitotic fidelity in the preimplantation embryoSemantic proximity Read ↗

Ectopic activation of the polar body extrusion pathway triggers cell fragmentation in preimplantation embryosSemantic proximity Read ↗

Branching out in different directions: Emerging cellular functions for the Arp2/3 complex and WASP-family actin nucleation factorsSemantic proximity Read ↗

Cell fragmentation in mouse preimplantation embryos induced by ectopic activation of the polar body extrusion pathwaySemantic proximity Read ↗

Activation of ADF/cofilin by phosphorylation-regulated Slingshot phosphatase is required for the meiotic spindle assembly in Xenopus laevis oocytes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.