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Article

JMY is required for asymmetric division and cytokinesis in mouse oocytes

25 Jan 2011

Abstract excerpt

JMY is a transcriptional co-factor of p53. Latest work has revealed that JMY is also an actin nucleation factor that regulates new filament assembly and activates Arp2/3 complex in somatic cells; however, roles of JMY in mouse oocyte are unknown. Here we showed the expression and functions of JMY during mouse oocyte meiotic maturation. JMY mRNA is expressed largely from germinal vesicle to metaphase I stage, and...

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PMID: 21266449
DOI: 10.1093/molehr/gar006

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