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Article

Activation of ADF/cofilin by phosphorylation-regulated Slingshot phosphatase is required for the meiotic spindle assembly in Xenopus laevis oocytes.

Molecular biology of the cell - 1 Jun 2013

Iwase Shohei, Sato Ryuhei, De Bock Pieter-Jan, Gevaert Kris, Fujiki Saburo, Tawada Toshinobu, Kuchitsu Miyako, Yamagishi Yuka, Ono Shoichiro, Abe Hiroshi

Abstract excerpt

We identify Xenopus ADF/cofilin (XAC) and its activator, Slingshot phosphatase (XSSH), as key regulators of actin dynamics essential for spindle microtubule assembly during Xenopus oocyte maturation. Phosphorylation of XSSH at multiple sites within the tail domain occurs just after germinal vesic...

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Identifiers

PMID: 23615437
DOI: 10.1091/mbc.E12-12-0851
PMCID: PMC3681698

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23615437-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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