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Article

PAK4 Regulates Actin and Microtubule Dynamics during Meiotic Maturation in Mouse Oocyte

1 Jan 2019

Abstract excerpt

Meiotic maturation of oocyte is an important process for successful fertilization, in which cytoskeletal integrality takes a significant role. The p-21 activated kinases (PAKs) belong to serine/threonine kinases that affect wide range of processes that are crucial for cell motility, survival, cell cycle, and proliferation. In this study, we used a highly selective inhibitor of PAK4, PF-3758309, to investigate the...

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PMID: 31595158
DOI: 10.7150/ijbs.34718

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