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Article

ApoE ε4 Allele Related Alterations in Hippocampal Connectivity in Early Alzheimer's Disease Support Memory Performance.

Current Alzheimer research - 1 Jan 2017

De Marco Matteo, Vallelunga Annamaria, Meneghello Francesca, Varma Susheel, Frangi Alejandro F, Venneri Annalena

Abstract excerpt

BACKGROUND: Whether the presence of the Apolipoprotein E ε4 allele modulates hippocampal connectivity networks in abnormal ageing has yet to be fully clarified. OBJECTIVE: Allele-dependent differences in this pattern of functional connectivity were investigated in patients with very mild neurodegeneration of the Alzheimer's type, carriers and non-carriers of the ε4 allele. METHOD: A seed-based connectivity...

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Identifiers

PMID: 28176662
DOI: 10.2174/1567205014666170206113528

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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