Article
P-selectin polymorphisms' influences on P-selectin serum concentrations and on their familial correlation: the STANISLAS family study.
Journal of thrombosis and haemostasis : JTH - 1 Jun 2008
Marteau J B, Lambert D, Herbeth B, Marie B, Droesch S, Tregouet D A, Visvikis-Siest S
Abstract excerpt
BACKGROUND: P-selectin is an adhesion molecule known to be involved in the pathogenesis of several diseases through its major role in the initial phase of leukocytes recruitment during inflammation. However, genetic characterization of soluble P-selectin remains unclear. OBJECTIVES: In the STANISLAS cohort, we study the familial correlations of P-selectin levels and investigate the association of six P-selectin...
Topics
- Adult
- Cardiovascular Diseases
- Cell Adhesion
- Cohort Studies
- Family Health
- Female
- Genetic Variation
- Humans
- Inflammation
- Male
- Middle Aged
